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1

Novel amino linkers enabling efficient labeling and convenient purification of amino-modified oligonucleotides

Yasuo Komatsu, Naoshi Kojima, Maiko Sugino, Akiko Mikami, Ken Nonaka, Yumi Fujinawa, Takashi Sugimoto, Kousuke Sato, Kenichi Matsubara, Eiko Ohtsuka

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 232 KB

english, 2008

2

Efficient synthesis of oligonucleotide conjugates on solid-support using an (aminoethoxycarbonyl)aminohexyl group for 5′-terminal modification

Naoshi Kojima, Toshie Takebayashi, Akiko Mikami, Eiko Ohtsuka, Yasuo Komatsu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 456 KB

english, 2009

3

Quality of Raw Water for Drinking-Water Supply on the Ogasawara Islands -Focusing on Formation Potentials of Disinfection By-products-

TOCHIMOTO, Hiroshi, KOSUGI, Yuki, KONISHI, Hiroyuki, INOMATA, Akiko, MUTO, Chieko, KURITA, Masayuki, YAGUCHI, Kumiko, CHIBA, Hayato, OHTSUKA, Hiroyuki

Journal:

Journal of Japan Society on Water Environment

Year:

2010

Language:

english

File:

PDF, 2.21 MB

english, 2010

4

Evaluation of the potential allergenicity of the enzyme microbial transglutaminase using the 2001 FAO/WHO Decision Tree

Mona H. Pedersen, Tine K. Hansen, Eva Sten, Katsuya Seguro, Tomoko Ohtsuka, Akiko Morita, Carsten Bindslev-Jensen, Lars K. Poulsen

Journal:

Molecular Nutrition & Food Research

Year:

2004

Language:

english

File:

PDF, 838 KB

english, 2004

5

One-step generation of recombineering constructs by asymmetric-end ligation and negative selection

Masato Ohtsuka, Akiko Mizutani, Yukie Y. Kikuti, Jerzy K. Kulski, Masahiro Sato, Minoru Kimura, Masafumi Tanaka, Hidetoshi Inoko

Journal:

Analytical Biochemistry

Year:

2007

Language:

english

File:

PDF, 295 KB

english, 2007

6

Simultaneous determination of bromvalerylurea and allylisopropylacetylurea in human blood and urine by gas chromatography–mass spectrometry

Keiko Kudo, Akiko Kiyoshima, Yukio Ohtsuka, Noriaki Ikeda

Journal:

Journal of Chromatography B

Year:

2003

Language:

english

File:

PDF, 278 KB

english, 2003

7

A study of factors for successful splint capture of anteriorly displaced temporomandibular joint disc with disc repositioning appliance

Hiroshi Kurita, Akiko Ohtsuka, Kenji Kurashina, Sigvard Kopp

Journal:

Journal of Oral Rehabilitation

Year:

2001

Language:

english

File:

PDF, 136 KB

english, 2001

8

Type

Akiko Ishige, Hiroyuki Tanaka, Tetsuro Ueda, Mikio Ninomiya, Toshiya Ohtsuka

Journal:

Journal of Echocardiography

Year:

2011

Language:

english

File:

PDF, 288 KB

english, 2011

9

Enhanced reactivity of amino-modified oligonucleotides by insertion of aromatic residue

Naoshi Kojima, Maiko Sugino, Akiko Mikami, Ken Nonaka, Yumi Fujinawa, Isamu Muto, Kenichi Matsubara, Eiko Ohtsuka, Yasuo Komatsu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 262 KB

english, 2006

10

Efficacy of a mandibular manipulation technique in reducing the permanently displaced temporomandibular joint disc

Hiroshi Kurita, Kenji Kurashina, Akiko Ohtsuka

Journal:

Journal of Oral and Maxillofacial Surgery

Year:

1999

Language:

english

File:

PDF, 576 KB

english, 1999

11

Effects of Light and Dark Environment on Regeneration of Carp Optic Nerves

MARI DEZAWA, AKIKO OHTSUKA, YUKIO SHIMODA, EMIKO ADACHI-USAMI, JOHN D. STEEVES, EISUKE EGUCHI

Journal:

Experimental Eye Research

Year:

1998

Language:

english

File:

PDF, 1021 KB

english, 1998

12

Evaluation of disk capture with a splint repositioning appliance: Clinical and critical assessment with MR imaging

Hiroshi Kurita, Kenji Kurashina, Hiroo Baba, Akiko Ohtsuka, Akira Kotani, Sigvard Kopp

Journal:

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology

Year:

1998

Language:

english

File:

PDF, 1.95 MB

english, 1998

13

Change of position of the temporomandibular joint disk with insertion of a disk-repositioning appliance

Hiroshi Kurita, Kenji Kurashina, Akiko Ohtsuka, Akira Kotani

Journal:

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology

Year:

1998

Language:

english

File:

PDF, 898 KB

english, 1998

14

The relationship between the degree of disk displacement and ability to perform disk reduction

Hiroshi Kurita, Akiko Ohtsuka, Hiroichi Kobayashi, Kenji Kurashina

Journal:

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology

Year:

2000

Language:

english

File:

PDF, 35 KB

english, 2000

15

Clinical trial of a method for confirming the effects of spinal anesthesia in patients with spinal cord injury

Takatsuki, Akiko, Ohtsuka, Masahide

Journal:

Journal of Anesthesia

Year:

2012

Language:

english

File:

PDF, 149 KB

english, 2012

16

Application of High-Field Superconducting Magnet to Protein Crystallization

Hitoshi Wada, Noriyuki Hirota, Shinji Matsumoto, Hidehiko Okada, Motosuke Kiyohara, Takahiro Ode, Masaru Tanokura, Akira Nakamura, Jun Ohtsuka, Akiko Kita, Nobutaka Numoto, Tatsuki Kashiwagi, Ei-ichir

Journal:

Physics Procedia

Year:

2012

Language:

english

File:

PDF, 2.01 MB

english, 2012

17

Construction of Highly Reactive Probes for Abasic Site Detection by Introduction of an Aromatic and a Guanidine Residue into an Aminooxy Group

Kojima, Naoshi, Takebayashi, Toshie, Mikami, Akiko, Ohtsuka, Eiko, Komatsu, Yasuo

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 141 KB

english, 2009

18

Diastolic suction in heart failure: Impact of left ventricular geometry, untwist, and flow mechanics

Nogami, Yoshie, Ishizu, Tomoko, Atsumi, Akiko, Yamamoto, Masayoshi, Nakamura, Akihiro, Machino-Ohtsuka, Tomoko, Kawamura, Ryo, Seo, Yoshihiro, Aonuma, Kazutaka

Journal:

Year:

2014

Language:

english

File:

PDF, 550 KB

english, 2014

19

Transmural Compensation of Myocardial Deformation to Preserve Left Ventricular Ejection Performance in Chronic Aortic Regurgitation

Iida, Noriko, Seo, Yoshihiro, Ishizu, Tomoko, Nakajima, Hideki, Atsumi, Akiko, Yamamoto, Masayoshi, Machino-Ohtsuka, Tomoko, Kawamura, Ryo, Enomoto, Mami, Kawakami, Yasushi, Aonuma, Kazutaka

Journal:

Journal of the American Society of Echocardiography

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

20

Prognostic significance of remaining severe left ventricular diastolic dysfunction after cardiac resynchronizaion therapy

Yamamoto, Masayoshi, Seo, Yoshihiro, Kawamatsu, Naoto, Sato, Kimi, Sugano, Noriaki, Atsumi, Akiko, Harimura, Yoshie, Machino-Ohtsuka, Tomoko, Sakamaki, Fumiko, Ishizu, Tomoko, Miyauchi, Takashi, Aonum

Journal:

Year:

2013

Language:

english

File:

PDF, 44 KB

english, 2013

21

Identification, expression and characterization of rat isoforms of the serum response factor (SRF) coactivator MKL1

Ishikawa, Mitsuru, Shiota, Jun, Ishibashi, Yuta, Hakamata, Tomoyuki, Shoji, Shizuku, Fukuchi, Mamoru, Tsuda, Masaaki, Shirao, Tomoaki, Sekino, Yuko, Ohtsuka, Toshihisa, Baraban, Jay M., Tabuchi, Akiko

Journal:

Year:

2013

Language:

english

File:

PDF, 1.44 MB

english, 2013

22

Feasibility of left ventricular volume measurements by three-dimensional speckle tracking echocardiography depends on image quality and degree of left ventricular enlargement: Validation study with cardiac magnetic resonance imaging

Kawamura, Ryo, Seo, Yoshihiro, Ishizu, Tomoko, Atsumi, Akiko, Yamamoto, Masayoshi, Machino-Ohtsuka, Tomoko, Nakajima, Hideki, Sakai, Satoshi, Tanaka, Yumiko Oishi, Minami, Manabu, Aonuma, Kazutaka

Journal:

Journal of Cardiology

Year:

2014

Language:

english

File:

PDF, 1.45 MB

english, 2014

23

Novel dyssynchrony evaluation by M-mode imaging in left bundle branch block and the application to predict responses for cardiac resynchronization therapy

Sakamaki, Fumiko, Seo, Yoshihiro, Atsumi, Akiko, Yamamoto, Masayoshi, Machino-Ohtsuka, Tomoko, Kawamura, Ryo, Yamasaki, Hiro, Igarashi, Miyako, Sekiguchi, Yukio, Ishizu, Tomoko, Aonuma, Kazutaka

Journal:

Journal of Cardiology

Year:

2014

Language:

english

File:

PDF, 1.24 MB

english, 2014

24

Efficacy, Safety, and Outcomes of Catheter Ablation of Atrial Fibrillation in Patients With Heart Failure With Preserved Ejection Fraction

Machino-Ohtsuka, Tomoko, Seo, Yoshihiro, Ishizu, Tomoko, Sugano, Akinori, Atsumi, Akiko, Yamamoto, Masayoshi, Kawamura, Ryo, Machino, Takeshi, Kuroki, Kenji, Yamasaki, Hiro, Igarashi, Miyako, Sekiguch

Journal:

Journal of the American College of Cardiology

Year:

2013

Language:

english

File:

PDF, 878 KB

english, 2013

25

CACNA1A variants may modify the epileptic phenotype of Dravet syndrome

Ohmori, Iori, Ouchida, Mamoru, Kobayashi, Katsuhiro, Jitsumori, Yoshimi, Mori, Akiko, Michiue, Hiroyuki, Nishiki, Teiichi, Ohtsuka, Yoko, Matsui, Hideki

Journal:

Neurobiology of Disease

Year:

2013

Language:

english

File:

PDF, 1.26 MB

english, 2013

26

Generation of an Abasic Site in an Oligonucleotide by Using Acid-Labile 1-Deaza-2‘-deoxyguanosine and Its Application to Postsynthetic Modification

Kojima, Naoshi, Sugino, Maiko, Mikami, Akiko, Ohtsuka, Eiko, Komatsu, Yasuo

Journal:

Organic Letters

Year:

2005

Language:

english

File:

PDF, 73 KB

english, 2005

27

Prognostic significance of persistent restrictive filling pattern after cardiac resynchronization therapy

Yamamoto, Masayoshi, Seo, Yoshihiro, Ishizu, Tomoko, Kawamatsu, Naoto, Sato, Kimi, Sugano, Akinori, Atsumi, Akiko, Harimura, Yoshie, Machino-Ohtsuka, Tomoko, Sakamaki, Fumiko, Aonuma, Kazutaka

Journal:

Journal of Echocardiography

Year:

2015

Language:

english

File:

PDF, 418 KB

english, 2015

28

Attentive tracking of moving objects in real 3D space

Ur Rehman, Anis, Kihara, Ken, Matsumoto, Akiko, Ohtsuka, Sakuichi

Journal:

Vision Research

Year:

2015

Language:

english

File:

PDF, 740 KB

english, 2015

29

P.28: Hue-Blending Method: Improved Red-Green Color Segregation Capability for Dichromacy Support

Hira, Shyoko, Matsumoto, Akiko, Kihara, Ken, Ohtsuka, Sakuichi, Iga, Koichi

Journal:

SID Symposium Digest of Technical Papers

Year:

2013

Language:

english

File:

PDF, 2.11 MB

english, 2013

30

Homozygous deletion of DIS3L2 exon 9 due to non-allelic homologous recombination between LINE-1s in a Japanese patient with Perlman syndrome

Higashimoto, Ken, Maeda, Toshiyuki, Okada, Junichiro, Ohtsuka, Yasufumi, Sasaki, Kensaku, Hirose, Akiko, Nomiyama, Makoto, Takayanagi, Toshimitsu, Fukuzawa, Ryuji, Yatsuki, Hitomi, Koide, Kayoko, Nish

Journal:

European Journal of Human Genetics

Year:

2013

Language:

english

File:

PDF, 307 KB

english, 2013

31

Enlargement of the left atrium is associated with increased infiltration of immune cells in patients with atrial fibrillation who had undergone surgery

Yamashita, Takeshi, Sekiguchi, Akiko, Suzuki, Shinya, Ohtsuka, Takayuki, Sagara, Koichi, Tanabe, Hiroaki, Kunihara, Takashi, Sawada, Hitoshi, Aizawa, Tadanori

Journal:

Journal of Arrhythmia

Year:

2015

Language:

english

File:

PDF, 3.29 MB

english, 2015

32

Prevalence and Clinical Determinants of Left Atrial Appendage Thrombus in Patients with Atrial Fibrillation Prior to Pulmonary Vein Isolation

Nishikii-Tachibana, Makiko, Murakoshi, Nobuyuki, Seo, Yoshihiro, Xu, DongZhu, Yamamoto, Masayoshi, Ishizu, Tomoko, Atsumi, Akiko, Machino-Ohtsuka, Tomoko, Kuroki, Kenji, Yamasaki, Hiro, Igarashi, Miya

Journal:

The American Journal of Cardiology

Year:

2015

Language:

english

File:

PDF, 335 KB

english, 2015

33

Psychological Issues in Heart Failure Patients Who Received Implantable Cardioverter-Defibrillator

Rahmawati, Anita, Chishaki, Akiko, Ohkusa, Tomoko, Sawatari, Hiroyuki, Tsuchihashi-Makaya, Miyuki, Ohtsuka, Yuko, Nakai, Mori, Miyazono, Mami, Hashiguchi, Nobuko, Sakurada, Harumizu, Takemoto, Masao,

Journal:

Journal of Cardiac Failure

Year:

2015

Language:

english

File:

PDF, 113 KB

english, 2015

34

A Simple and Sensitive Method for Detecting Major Mutations Within the Tyrosine Kinase Domain of the Epidermal Growth Factor Receptor Gene in Non???small-cell Lung Carcinoma

Ohnishi, Hiroaki, Ohtsuka, Kouki, Ooide, Akiko, Matsushima, Satsuki, Goya, Tomoyuki, Watanabe, Takashi

Journal:

Diagnostic Molecular Pathology

Year:

2006

Language:

english

File:

PDF, 428 KB

english, 2006

35

Clinico-Pathological and Biological Significance of Tyrosine Kinase Domain Gene Mutations and Overexpression of Epidermal Growth Factor Receptor for Lung Adenocarcinoma

Ohtsuka, Kouki, Ohnishi, Hiroaki, Furuyashiki, Go, Nogami, Hiroshi, Koshiishi, Yoshihiko, Ooide, Akiko, Matsushima, Satsuki, Watanabe, Takashi, Goya, Tomoyuki

Journal:

Journal of Thoracic Oncology

Year:

2006

Language:

english

File:

PDF, 562 KB

english, 2006

36

Influence of primary and secondary prevention indications on anxiety about the implantable cardioverter-defibrillator

Rahmawati, Anita, Chishaki, Akiko, Ohkusa, Tomoko, Sawatari, Hiroyuki, Tsuchihashi-Makaya, Miyuki, Ohtsuka, Yuko, Nakai, Mori, Miyazono, Mami, Hashiguchi, Nobuko, Sakurada, Harumizu, Takemoto, Masao,

Journal:

Journal of Arrhythmia

Year:

2016

Language:

english

File:

PDF, 318 KB

english, 2016

37

Multicentric Castleman's Disease Associated with Inherited Epidermolysis Bullosa

Kawakami, Yoshio, Nishibu, Akiko, Kikuchi, Satoshi, Ohtsuka, Mikio, Nakamura, Koichiro, Nozawa, Yoshihiro, Abe, Masafumi, Iwatsuki, Keiji, Kaneko, Fumio

Journal:

The Journal of Dermatology

Year:

2003

Language:

english

File:

PDF, 311 KB

english, 2003

38

In-situ and real-time growth observation of high-quality protein crystals under quasi-microgravity on earth

Nakamura, Akira, Ohtsuka, Jun, Kashiwagi, Tatsuki, Numoto, Nobutaka, Hirota, Noriyuki, Ode, Takahiro, Okada, Hidehiko, Nagata, Koji, Kiyohara, Motosuke, Suzuki, Ei-ichiro, Kita, Akiko, Wada, Hitoshi,

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.50 MB

english, 2016

39

Psychotropic Drugs and Local Anesthetics Restore Cardiolipin-Inhibited Mammalian DNA Topoisomerase I Activity.

SHAH, Gulzar, KATAOKA, Kazuhiro, UENO, Akiko, OHTSUKA, Yoshihisa, MIZUSHIMA, Tohru, SEKIMIZU, Kazuhisa

Journal:

Biological & Pharmaceutical Bulletin

Year:

1997

File:

PDF, 581 KB

1997

40

Tissue Doppler Imaging Dyssynchrony Parameter Derived From the Myocardial Active Wall Motion Improves Prediction of Responders for Cardiac Resynchronization Therapy

Sakamaki, Fumiko, Seo, Yoshihiro, Ishizu, Tomoko, Yanaka, Satomi, Atsumi, Akiko, Yamamoto, Masayoshi, Machino-Ohtsuka, Tomoko, Kawamura, Ryo, Yamasaki, Hiro, Igarashi, Miyako, Yoshida, Kentaro, Sekigu

Journal:

Circulation Journal

Year:

2012

Language:

english

File:

PDF, 1.84 MB

english, 2012

41

Gender Disparities in Quality of Life and Psychological Disturbance in Patients With Implantable Cardioverter-Defibrillators

Rahmawati, Anita, Chishaki, Akiko, Sawatari, Hiroyuki, Tsuchihashi-Makaya, Miyuki, Ohtsuka, Yuko, Nakai, Mori, Miyazono, Mami, Hashiguchi, Nobuko, Sakurada, Harumizu, Takemoto, Masao, Mukai, Yasushi,

Journal:

Circulation Journal

Year:

2013

Language:

english

File:

PDF, 343 KB

english, 2013

42

Application of 3-Dimensional Speckle Tracking Imaging to the Assessment of Right Ventricular Regional Deformation

Atsumi, Akiko, Ishizu, Tomoko, Kameda, Yuri, Yamamoto, Masayoshi, Harimura, Yoshie, Machino-Ohtsuka, Tomoko, Kawamura, Ryo, Enomoto, Mami, Seo, Yoshihiro, Aonuma, Kazutaka

Journal:

Circulation Journal

Year:

2013

Language:

english

File:

PDF, 1.69 MB

english, 2013

43

Significant Improvement of Left Atrial and Left Atrial Appendage Function After Catheter Ablation for Persistent Atrial Fibrillation

Machino-Ohtsuka, Tomoko, Seo, Yoshihiro, Ishizu, Tomoko, Yanaka, Satomi, Nakajima, Hideki, Atsumi, Akiko, Yamamoto, Masayoshi, Kawamura, Ryo, Koshino, Yuki, Machino, Takeshi, Kuroki, Kenji, Yamasaki,

Journal:

Circulation Journal

Year:

2013

Language:

english

File:

PDF, 2.02 MB

english, 2013

44

Hispidospermidin, a novel phospholipase C inhibitor produced by Chaetosphaeronema hispidulum (Cda) Moesz NR 7127. II. Isolation, characterization and structural elucidation.

OHTSUKA, TATSUO, ITEZONO, YOSHIKO, NAKAYAMA, NOBORU, SAKAI, AKIKO, SHIMMA, NOBUO, YOKOSE, KAZUTERU, SETO, HARUO

Journal:

The Journal of Antibiotics

Year:

1994

Language:

english

File:

PDF, 505 KB

english, 1994

45

Eucapnic Hyperventilation-Induced Bronchoconstriction in Rabbits.

KOYAMA, SHINICHIRO, OHTSUKA, AKIKO, HORIE, TAKASHI

Journal:

The Tohoku Journal of Experimental Medicine

Year:

1992

Language:

english

File:

PDF, 911 KB

english, 1992

46

Global and Regional Right Ventricular Function Assessed by Novel Three-Dimensional Speckle-Tracking Echocardiography

Ishizu, Tomoko, Seo, Yoshihiro, Atsumi, Akiko, Tanaka, Yumiko Oishi, Yamamoto, Masayoshi, Machino-Ohtsuka, Tomoko, Horigome, Hitoshi, Aonuma, Kazutaka, Kawakami, Yasushi

Journal:

Journal of the American Society of Echocardiography

Year:

2017

Language:

english

File:

PDF, 1.95 MB

english, 2017

47

STUDY ON CHARACTERISTICS AND CONDITION ASSESSMENT OF BUILDING SYSTEM OF 100 YEARS OLD WAREHOUSE WITH TIMBER AND REINFORCED CONCRETE AS HYBRID STRUCTURE

OHTSUKA, Akiko, IMAMOTO, Kei-ichi, NOGUCHI, Takafumi, KANEMATSU, Manabu, HAMASAKI, Hitoshi, KIYOHARA, Chizuru, SHIKI, Yuichi, KINOSE, Toru

Journal:

AIJ Journal of Technology and Design

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

48

A long-term survival case treated with conversion surgery following chemotherapy after diagnostic metastasectomy for pancreatic cancer with synchronous liver metastasis

Shimura, Mitsuhiro, Mizuma, Masamichi, Hayashi, Hiroki, Mori, Akiko, Tachibana, Tomoyoshi, Hata, Tatsuo, Iseki, Masahiro, Takadate, Tatsuyuki, Ariake, Kyohei, Maeda, Shimpei, Ohtsuka, Hideo, Sakata, N

Journal:

Surgical Case Reports

Year:

2017

Language:

english

File:

PDF, 1.14 MB

english, 2017

49

O1-21-2Hyperprogression during nivolumab (Nivo) or irinotecan (IRI) as salvage-line in patients with metastatic gastric cancer

Sugimoto, Naotoshi, Ohtsuka, Toshiyuki, Fujiishi, Koto, Kusakabe, Akira, Hasegawa, Akiko, Nishio, Minako, Fujisawa, Fumie, Yagi, Toshinari, Imamura, Fumio

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 89 KB

english, 2018

50

FBXW7 modulates malignant potential and cisplatin-induced apoptosis in cholangiocarcinoma through NOTCH1 and MCL1

Mori, Akiko, Masuda, Kunihiro, Ohtsuka, Hideo, Shijo, Masahiro, Ariake, Kyohei, Fukase, Koji, Sakata, Naoaki, Mizuma, Masamichi, Morikawa, Takanori, Hayashi, Hiroki, Nakagawa, Kei, Motoi, Fuyuhiko, Na

Journal:

Year:

2018

Language:

english

File:

PDF, 1.00 MB

english, 2018